Malegra 100 is a medication primarily used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, a potent ingredient that belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. To understand how Malegra 100 works, it's essential to delve into its mechanism of action and the physiological processes involved.
When a man experiences sexual arousal, certain chemical signals are released in the body, leading to the relaxation of smooth muscles in the erectile tissue of the penis. This relaxation allows increased blood flow into the penile arteries, resulting in an erection. However, in individuals with ED, there is an enzymatic action that restricts the blood flow, leading to difficulty in achieving or maintaining an erection.
Malegra 100 works by inhibiting the action of the PDE5 enzyme, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). Normally, cGMP helps in dilating blood vessels and improving blood flow to the penis during sexual stimulation. However, PDE5 breaks down cGMP, causing a decrease in its levels and impeding the normal erectile response.
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